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Sunday, 16 December 2018

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Well fessed up, at last.

Been doing my best to stir up your band of country-bumpkins and keep them entertained, but there's no replacement for your stream of observational posts.

Let's get you zapped and back asap.

SoD

All the very best to you & Lady DD in the future.

It must be a comfort to have one such as SoD available to keep you entertained with his laughably inaccurate prognostications...

I had my suspicions when you mentioned 'dehydration'. Three days before Christmas 2008, I was diagnosed with prostate cancer myself. My Father had it and the trait does pass from father to son. Daily trips to any hospital are tiresome but in the winter even more so. Lawrence, take note and keep a check in the usual way.

Robert

David

Do like the doctors say and get well.

Glowing in the dark won't be so bad, think of the electricity you will save!

All the best.

You are not alone. In Germany the drinking toast used to be 'Prost!' - now among elderly gents it is 'Prostata!'

Having jumped out of aeroplanes for a job you will have no difficulty coping with the Great Ming's ray gun.

FoS

My best wishes to you too. You may well "Glow in the dark" but I hope you will cope without your methotrexate for a few weeks. Pain is so draining, as you say. My sympathy to Lady Duff who will have to put up with you!!

Keep your pecker up (no pun intended) X

Get well soon Mr Duff. What with Mark Gronmark not doing so well also, where will I find expert analysis and fine wit ?

The prostate gland. So much for "intelligent design", eh? In the UK chances are excellent something else will eventually get you. All the same best of luck, David.

Like Robert says David, my Dad had it and now me too. Perhaps not surprisingly (given my many broken bones) although of the osteo variety, arthritis too.

Dad went the rads way but, along with "my medical team" (probably owing to I'd already signed onto a study helped) we decided on a different route.

The UK got a version of the drug Alprostadil™ to hand? My girlfriend loves the stuff. Smiles all round.

🤞 take care

Wishing you all the best. I hope your treatment goes well and you are soon back on your drug of choice.

I'm going in for a test regarding my prostate the day after Boxing Day. It will apparently involve a large bearded Irishman putting his finger up my back passage. I can't afford to go private, otherwise I would have asked for the receptionist to do it.

Best wishes.

I hope all goes well as I'm sure it will. A chap I walk with had prostate cancer about a year ago. He had the death ray and chemo treatment and is now fine, walking as well as ever.

I too send my sentiments.

Whyaxye,
Be sure you can account for BOTH hands of that 'bearded Irishman' during the procedure.

As a fellow sufferer of both RA and OA and Methotrexate user I know of what you speak. I'm also having my prostate investigated - OO, ER, Missus and calm myself with what I read some time ago - most men die with prostate cancer, very few die of it. Take care and keep us updated.

Here's two to look into if it comes your way or anyone you know.

1. Irreversible Electroporation (NanoKnife).

Tiny wires with micro electrodes on the ends are threaded into the area so as to surround the tumour with a 3D polygon of electrode points.

The quack then switches on 2000 Volts for 20 minutes and fries the little fker. I suggested he invites family members and loved ones in to be the ones to throw the switch.

For some bio-scientific reason the electricity flows only through the tumour cells. It breaks down the surface of the cancer cells, so over the coming days they commit cell suicide, called aptosis.

That means the tumour withers away allowing surrounding normal cells to grow back more smoothly than surgery.

Astonishingly the procedure is not far off being day surgery. They do knock you out but most go home the next day.

In the UK it's around £10k at the Princess Grace Hospital London. The NHS trialled it but seem to have stopped. The Yeovil NHS mob had never heard of it.

Unfortunately for the Gaffer, the tumour hasn't got enough space around it in the prostate. The quack needs some clearance to lodge the electrodes in.

This technique is available for tumours in other organs too.

One to keep in the back of one's mind.

2. Seabed bacteria and lasers.

No, SoD's not off on one again. But granted this one's in the future pipeline.

The bacteria on the seabed are super-duper responsive to light, being as there is very little light in their neighbourhood.

So what you do is inject the patient with these bacteria. They travel harmlessly around the blood vessels, not doing much due to the lack of light.

Then you thread those wires into and around the tumour, only this time they're fibre optic cables.

Then you invite the family and loved ones in again, and they switch on the laser light that flows down the fibre cables and lights the tumour up like a fking Xmas tree.

You don't want to be lit up like an Xmas tree when those light starved seabed bacteria find you, no siree. They munch the tumour alive in a few days, again, neatly allowing the surrounding flesh to settle back into the void where the tumour was.

Then you simply turn off the laser and pop some antibiotics to clear up the seabed bugs (seems a shame to kill off those little hero's).

Can you even start to contemplate the huge lateral thinking creativity of the mind who thought of that? Seabed bacteria, laser = treatment for cancer. Wow.

https://www.google.com/amp/s/mobile.reuters.com/article/amp/idUSKBN14916E

Rereading that articles I see it's slightly different from my description, but you get the point.

Prof Mark Emberton is the guy I took the Gaffer to see ref the Irreversible Electroporation at Princess Grace Hospital in London. He is also involved in the seabed bacteria / laser approach.

Some pointers, perhaps, for anyone starting off down this road.

However, Prof Emberton explained the bog standard NHS approach of hormone treatment to starve the tumour followed by targeted radiotherapy (the "death ray", as the Gaffer calls it) is very effective. The main advantage of the two described is the way they target the tumour more exactly and therefore reduce the risks of side effects.

SoD

Wot?

SoD (& by Extension),

"Not enough space" & "needs clearance" eh?

Here, VA is doing a study combining the effects of "a certain selective agent" with a very particular, newly developed 5–alpha-reductase inhibitor. Early observations show promise and as The Jannie assures above ...

Might ask y'alls Professor Emberton if'n he's got any contacts in the States. (And it is my understanding, it must be said, as this therapeutic trial has yet to be "approved" ... there's some preliminary studies must be done on the volunteer.)

Whitewall:

If I can see both his hands and there's something still in situ, so to speak, then I'm going to cry all the way home.

I hope the Irishman is forgiving about the "backstop" situation.

I had a feeling something was afoot! I am glad you are comfortable with us to share. I will certainly keep you, memsahib, and even SOD in my thoughts and prayers. Post your entertaining, thoughtful, and educational muses when you can. And know that there are more than just your readers thinking of you. I think of you as my friend.
Take care of yourself. Please.

Dear Duffers - all the best with your death ray and all the rest and hoping you'll be back to regale us with your customary wit and insight in a very short time.

JK, sorry for the delay, just got back from a long day out.

I'll ping Prof Emberton's team about NanoKnife in the US and cc you in. I'll put details on here too for any others interested.

SoD

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